How tirzepatide works
Tirzepatide is a dual GLP-1 and GIP receptor agonist. It produces strong weight loss and glycemic control, but the same mechanisms that slow stomach emptying create the conditions for severe gastrointestinal injury in some patients.
Qualifying injuries
Gastroparesis, severe pancreatitis, intestinal obstruction or ileus, gallbladder disease requiring surgery, and aspiration during anesthesia are the principal injuries under investigation.